Actinic Keratosis (AK)
VivoSight imaging of AK and sub-clinical AK
VivoSight enables assessment of AK lesions providing the following benefits:
- VivoSight images show markers specific to AK
- OCT pre-scanning shows lesion details which can aid in the treatment selection
- Visualization of sub-clinical lesions
- Understand local and field spread of overall AK
- Monitor treated site through follow-up VivoSight scanning
- Opportunity to offer premium maintenance treatments (laser/PDT) and control recurrences through periodic VivoSight follow-ups
VivoSight Presentations of AK
Actinic keratosis presents with atypical thickening of the epidermis. Thickening of the epidermis at the lesion edges is usually focused to the stratum corneum layer
Case 1: Topical treatment of subclinical AK with ingenol mebutate gel
Case 2: Topical treatment with Imiquimod 3.75% cream.
- Treatment of moderate AK lesion with imiquimod 3.75% cream. Note restored epidermis and dermo-epidermal junction after therapy regimen . Images courtesy of Reinhold 
Case 3: Fractional laser-assisted treatment of AK. Periodic follow-up with VivoSight.
- Fractional laser alone treatment, and laser-assisted PDT treatment of AK also leads to a noticeable cosmetic effect 
- Periodically (annually) scheduled follow-up visits can use VivoSight to check for AK recurrences or subclinical lesions. Opportunity to offer subsequent prophylactic laser resurfacing (Sciton Halo ) as annual, premium maintenance treatment.
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8. Onkoderm04_Sept2012.pdf. Interview mit Prof. Thomas Dirschka, Düsseldorf, und Prof. Uwe Reinhold, Bonn